Safety. Australian Shepherds have a slightly lower incidence, with 50% being affected . Id like to have a Border Collie one day, but as I have some health issues Im not sure I could keep up with one. Ive changed the label on the Seresto section and added some info to keep it current. Sugar is a great name for a Collie as they really are such sweethearts. Kills 5 types of ticks. After 1 emergency vet visit and a number of consultations with our primary care vet, we took him off simparica. Are you also on Instagram, by chance? The tail curling and pacing lasted over a week. One thing about Credelio is that it only breaks the flea life cycle at one point (kills adult fleas only after they bite the dog), so you may want to use a natural flea & tick repellent spray to increase its effectiveness. Nexgard and Simparica. (Some of the links lead to peer-reviewed scientific articles, so have fun with those if you want the bare, dusty facts.). According to a thorough study conducted on MDR1-affected dogs, Interceptor and its more affordable generic, MilbeGuard, rank high in ML safety due to their use of the compound called milbemycin oxime. To make dosing easy, it's available for dogs in six sizes based on body weight range: Gold: 2.8-5.5 pounds. Besides safety, Revolution is an attractive option because of its ease of application (topical squeeze-on tube) and versatility in treating heartworm, fleas, dog ticks, sarcoptic mange, and even ear mites. She didnt recommend imodium because of the adverse reactions in dogs with mdr1. (Same active ingredients in both.) Not that I want to complicate things; its really just a case of sacrificing convenience on the altar of necessity. Where can I get them tested for MDR1 resistance. This is a new extensively tested product now available in Australia that provides optimal protection for your dog. LIST OF DRUGS THAT CAUSE SENSITIVITY TO DOGS WITH MDR1 MUTATION. She has a close cat buddy, so Im scared to use another spot-on that is poisonous to cats. For my Aussie mix, Ive had success using Advantix II. Though all of these medicines had previously been approved by FDA scientists, now data received by the agency indicates that some animals receiving Bravecto, Nexgard, or Simparica have experienced adverse events such as muscle tremors, ataxia, and seizures.. My 2 Collies both had negative skin reactions to Advecta 3D, unfortunately. In a laboratory study, the product was well tolerated in dogs with a deficient multidrug-resistance- protein 1 (MDR1 -/-) following single oral administration at 3 times the recommended dose. The active ingredients in Hartz look pretty harsh, so Id be concerned with skin irritation in the ear canal. Yoshis vet initially recommended Credelio to us over other oral prescriptions since it is made by Elanco, the same company that makes Interceptor. Personally, my Roughs have sensitive skin plus I have a household cat, so Id try Frontline Gold first. I tried to review a variety of the most well-known parasite protection products out there, but if I left out any you are curious about, leave a comment below! Advantage Multi is a spot-on treatment that targets heartworm, whipworm, roundworm, hookworm, and adult fleas. Vectras brag is that it repels and kills fleas, five kinds of ticks, flies, mosquitoes, and mites; however, its use is not worth its risk. Frontline Plus targets four kinds of ticks, fleas (including eggs and larvae), lice, and mites that cause sarcoptic mange. Tap to zoom. I just dont know what to do about heartworm treatment and wonder if Interceptor instead of Interceptor Plus would be a better option or more of the same. I am currently fostering 3 rescued puppy mill border collie females with sarcoptic mange. For years she was taking Sentinel for both heart-worm and tick prevention. When reading about Seresto, their website said it doesnt work well on dogs with heavy coats, ie. So, what do you think of Parastar Plus? enough to have 4 dogs like I do! The manufracturers website lists many different kinds of ticks, and people on this thread talk about using FrontLine for ticks. I cant speak from personal experience on this, but the Seresto effectiveness/safety question has come up in an international Rough Collies group Im part of on Facebook. 2022 Collie Chatter. Honestly, Id use it even if it was completely ineffective, because it makes my dogs smell delicious. Roxie has never been tested, but she is Dashs niece so probably also mutant/normal if I were to guess. Thank you for fostering! One observation: You mention that Credelio has fewer reported seizures (6 in as many months) than other drugs in the isoxazaline class. It probably is the safest as it is aimed only at preventing heartworm. Its simpler to identify medicines by their components, since many of them are essentially the same thing marketed under different brand names. While this study conducted on twenty MDR1-affected Collies did not reveal any adverse reactions when the dogs were given low doses of Milbemycin Oxime combined with Spinosad, the Washington State University of Veterinary Medicine does advise that some of the combination flea+heartworm preventive products (those containing spinosad) should be used cautiously in dogs that are MDR1 mutant/normal because of a risk of serious drug-drug interactions.. Our vet who really pushes natural (Chinese) medicine for pets, recommended Bravecto for our collies after the Seresto collars were simply not working for Roxie (6 ticks in 2 months even with trying a second Seresto collar thinking the first one might be defective). THANK YOU, THANK YOU, THANK YOU! Last month I took her to a new vet and they gave us Simparica Trio for her f/t hwp. Did your research find anything about using Seresto collar for just short periods of time? Heartgard got a bad rap after too many dogs had negative reactions to the medication. Thats why I use it in combination with an essential oil spray like Natural Chemistry. My border collie started having seizures (he was on Bravecto AND Sentinel) and the vet never said anything about the gene mutation. Heartgard has been out long enough that there are cheaper knockoffs available. That averages out to about 212 deaths per year. I have a 8 yr old MAS/Aussie who is MDR1 +/+ and I have her on Trifexis and have had no issues to date. My question is about Capstar. I gave a mini aussie and a minnie aussie/border collie mix. ( I had to get a different vet for my pup because my current vet couldnt get him in to start his vacines for 2.5 months. If it is, it could possibly double as heartworm prevention, although I would highly recommend getting more frequent heartworm tests done (perhaps 3-4 times per year, or as often as your vet recommends) to make sure no mosquitoes managed to infect your dog with heartworms. I like Frank so much that I had to give him his own story. For the majority of dogs, Advecta is probably fine! Thats a good point about the potentially smaller user sample size for Credelio, since its a newer medication that hasnt been out as long as the others. Im just looking for advice as to tick prevention medication. 1 x 5mg tablet for 2.8 to 5.5 pounds. Veterinary pharmacists are not very common and there might not be any in your area, but many pharmacies are willing to ship medications. The vet thought he would be nice and put Advantage Multi on our cats. It can be used to destroy bedbugs, cockroaches, ants, and even fleas. Are you referring to Advantage Multi, Advantage II, or a different product I didnt cover in the article? For Guss veterinarian, Credelio is now the only member of the isoxazoline class that he will sell. Hi Debbie! (I did try to use it to deworm my cat without great success, but that could just be because I couldnt get him to ingest a complete dose at once.) From an MDR1 standpoint, Simparica is *technically* safe; but I am leery of it considering the FDA warning about isoxazolines (-laner medications) I discussed in the article. Most veterinarians in my area are still prescribing Bravecto, simply because they arent yet comfortable enough with Credelio. Those are both still very effective products, but have fewer horrror stories of terrible skin reactions. Rich Soil gives this excellent explanation of what DE is and how it works: the fossilized remains of marine phytoplankton. User warnings Wash hands after handling the product. I just picked out a beautiful tri color rough collie this morning! What an awesome article. We have an MDR1 heterozygous Aussie and this was the best breakdown of the meds we found. I realized that I just replied to another comment from you Im sorry you and your doubly sensitive girl are having such trouble trying to find products that work for her! Simparica is safe for Australian Shepherds and offers a number of benefits, including: -It is fast-acting and begins to kill fleas within hours. Thank You so much for your quick response Emily!! We do, however, have lots of deer ticks (also known as black legged ticks). Whats the best safest flea tick treatment for a collie puppy? Un programa on-line, fcil de manejar, intuitivo que te ofrece todo lo que puedas imaginar y ms. All but one (5 of 6) of the Simparica Trio-treated dogs were negative for D. immitis antigen and MF on day 180, while the remaining dog was positive for the antigen but negative for MF for this day. Simparica Trio is proven to kill 5 species of ticks. However, I officially can no longer recommend Seresto collars, since it is now known thatthey have caused seizures and death in dogs and even some reactions in humans who sleep with their dogs in their beds. If you havent yet tried Interceptor for heartworm prevention, I would suggest that for you. Im glad you found this information helpful. For the treatment and control of tick infestations with Amblyomma americanum (lone star tick) and Ixodes scapularis . They said Frontline Plus doesnt really work anymore like it used too. I would say you are right to be concerned, and Ill give some info why. Any thoughts on either of these? We recently switched our dogs to a new product called Simparica Trio. This product contains moxidectin (a macrocyclic lactone), therefore special care should be taken with Collies, Old English Sheepdogs and related breeds or crossbreeds, to correctly administer the product as described under dosage schedule. Im happy to hear you found it helpful! These can come in a few different forms: monthly spot-on, a disposable collar, or a spray. Ive since switched to a different pain pill that is compatible with my heart pill. According to the product description, side effects as a result of Trifexis are rare, but can be as severe as seizures or even a coma. Hope this helps! That way if a tick does make it past the essential oil barrier and bite, itll die anyway. You should still keep an eye on your pet when introducing new organic products. I love that it quickly kills adult fleas andfour kinds of ticks: American dog tick, brown dog tick, lone star tick, and black-legged tick. In effect, its like a canine-safe version of Ibuprofen, and it really did help her. My pleasure! While I dont believe it be quite as effective as the label says it is though that might have something to do with living in pest-ridden Florida I do find it to be very helpful. Mary. Corrosivity (The Environmental Protection Agency is responsible for approving external flea and tick products.) Hi Emily The collar releases no odor or residue, comes with a quick release catch to prevent accidental choking, and even has safety reflectors. (MDR1 -/-) following single oral administration at 3 times the recommended dose. In regard to natural products, Ive used some organic topicals, which Ill list later, that aresomewhat effective as repellents; but unfortunately I do not know of any natural pest control products that actually work as well as chemical-based ones. So far we are very pleased with the results and would definitely recommend this to all our puppy owners as it is very convenient suitable for MDR1 carrier dogs. The parasite protections that target multiple parasites with just one topical application or administration of a pill are extremely appealing due to their convenience. My plan is to adopt a senior Border to go with my lazy Roughs. Thank you so much for all your hard work and care given to writing this very informative and extremely important study greatly appreciate it , I would like to thank you for your very thorough but get to the point info of all these parasitic treatments We have a rough Collie I could not find any info on safe treatments without wading through a river of muck. Simparica Trio 11.1-22 lbs. My border collie/lab mix has a major seizure yesterday and has no history of seizures before this. But Ive given it a caution designation as it should not be given in combination with heartworm meds and is not safe for dogs who are at risk for seizures. Documented negative reactions were only provoked at higher-than-normal dosages and were comparatively mild, consisting of salivation, ataxia (dilated pupils), and depression. This product is an awesome all in one, monthly chewable tablet. We have two collies, Dash (8 yr old male) and Roxie (2.5 yr old female). they have caused seizures and death in dogs and even some reactions in humans who sleep with their dogs in their beds. Thanks Any of the -mectins are only safe for MDR1-prone breeds at the recommended dosage. A combination of -mectin in topical and oral form could definitely cause negative reactions if any of your foster puppies have MDR1. Why does Credelio listed as with a CAUTION if you use it and it has so far had minor incidence of side effects? Simparica TRIO is a monthly chew with triple protection against the three biggest threats facing our dogs today - fleas and ticks, intestinal worms and deadl. It was both well written, and concise. (For those who may be wondering, the mutant/normal designation means that a dog carries one copy of a gene and is a carrier, though not affected to the degree that a homozygous, or mutant/mutant, dog would be.) But remember, dogs can also be sensitive to essential oils just like my friend who is allergic to lavender so natural doesnt automatically mean best for your dog either. Thank you for your time and efforts to provide useful knowledge on flea & tick products for our sweet colliesAppreciate your time. While my pain levels went down, I noticed that my heart rate went up! Please tell me if I am wrong. Revolution and Stronghold even tested safe over the recommended monthly dosage for dogs with the MDR1 gene, and they hold the distinction of being the only heartworm meds that did not produce any negative drug reactions. It prevents flea and tick infestations. You might want to look at the information on Nexgard. Simparica TRIO for X-Large Dogs - 88 - 132 lbs - BROWN - 6 tablets (In Stock) $116.95: . The full indication is: "For dogs with, or at risk from, mixed external and internal parasitic infestations. Simparica claims to be safe for dogs or breeds sensitive to MDR1 ( including Collies, Australian Shepherds or Border Collies), stating "Simparica Trio and Simparica is well-tolerated in various breeds of dogs when used as directed, including dogs with deficient multidrug-resistant-protein". As the agency explained: Although FDA scientists carefully evaluate an animal drug prior to approval, there is the potential for new information to emerge after marketing, when the product is used in a much larger population. (New drugs continue to be highly monitored for the first three years following their release.). Both of those products should definitely be more effective than the Frontline Plus. There are other risks involving Ivermectin. Thankfully he recovered but my vet tells me Interceptor Plus is safe and he must have ingested something on his walk. You can even scatter some on your dogs bed. It is also used off-label to control sarcoptic mange and demodectic mange. Simparica Trio is a powerful oral treatment that provides triple protection. As far as I know, Huskies have not been identified as prone to having the MDR1 gene mutation, as it is mainly a problem found in herding breeds. I have two Rough Collies who are MDR1 carriers and an Aussie mix, so I have a vested interest in everything Ive researched. All Rights Reserved. Sarolaner, sold under the brand name Simparica, is an ectoparasiticide veterinary medication for the treatment of flea and tick infestations in dogs. Simparica TRIO Chews for Dogs 44-88 lbs (20.1-40 kg) - Green 6 Chews (11/2024 Expiry) Was: $115.99. However, as with any chemical compounds, caution is advised even with products deemed to be safe. I actually ended up choosing Interceptor Plus along with Credelio after looking at your research and getting some advice from fellow Aussie owners. Hi! If your Collie doesnt play like that, you should be fine. Select in Checkout Positive feedback keeps me writing! 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Work anymore like it used too didnt recommend imodium because of the isoxazoline class that he sell.
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